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Tadalafil in the UK was the third anti-ED treatment to enter the market. It has been affectionately dubbed ‘the weekend pill’ due to its 36-hour period of efficacy. Tadalafil in the UK was originally marketed under the brand name Cialis when used to treat ED as well as various other brand names when used in the treatment of benign prostatic hyperplasia and pulmonary arterial hypertension.
Cialis tablets treats ED by enlarging the blood vessels through a process known as vasodilation, thereby allowing for a greater quantity of blood to flow to the penis which results in an erection. This is possible because tadalafil inhibits the production of phosphodiesterase type 5 (PDE-5), an enzyme that breaks down the compound cyclic guanosine monophosphate (cGMP).
Cyclic GMP is a crucial substance for the erection process, as it is the compound that encourages vasodilation to occur. Generally, after an orgasm PDE-5 is released to decrease cGMP and therefore return the penis to its flaccid state.
However, if there is too much PDE-5 in the body pre-erection (or too little cGMP) the penis will not be able to become erect. Tadalafil in the UK has become so popular because it rectifies this issue by lowering PDE-5 and boosting cGMP. Now, once you are sexually stimulated you will achieve a rock-hard erection that is sure to please your lover and yourself.
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Alice JonesFounder