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Powiększenie Penisa
by on December 27, 2020
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While there is increasing evidence that nutritional supplements tabletki na powiększenie penisa improve particular semen parameters in particular groups of men, the evidence is derived mostly from small trials. Typically evidence from large trials, involving for example hundreds or thousands of participants, is needed before particular interventions (in this case, provision of nutritional supplements) can be recommended as treatment for health conditions (such as male factor infertility). Therefore, more research, involving greater numbers of men is needed to determine whether or not nutritional supplements improve semen quality before they can be recommended as a treatment for male factor infertility. It is also important to note that most evidence to date details associations between increased micronutrient intake and improved semen parameters, but not improved fertility (for example, the time it takes for a couple to conceive or the risk of miscarriage after conception). While improved semen quality should theoretically improve male fertility, there is to date no direct evidence that the semen quality improvements associated with increased micronutrient intake also improve fertility. Studies which investigate whether or not nutritional supplements improve time to pregnancy and other indicators of fertility are also needed. Currently there remains insufficient evidence on the effect of nutritional supplements on the fertility of human males to recommend them as therapy for male factor infertility. However, we do know from strong clinical evidence that a healthy diet (e.g. low in fat and containing plenty of fruit and vegetables) and lifestyle (with plenty of exercise), which protects against the development of obesity, diabetes and other chronic health conditions protects sperm health. Men who are concerned whether their nutritional intake is affecting their sperm health should therefore filmy pornograficzne focus on improving their diet and getting regular exercise, rather than taking nutritional supplements. For more information on sperm health, including factors affecting sperm health and investigations of sperm health, see Sperm Health. References 1. Royal College of Obstetricians and Gynaecologists. Fertility: Assessment and treatment for people with fertility problems – Clinical Guideline [online]. Royal College of Obstetricians and Gynaecologists, 2004. [cited 2010, March 10]. Available from URL: www.rcog.org.uk/womens-health/clinical-guidance/fertility-assessment-and-treatment-people-fertility-problems. 2. Ebisch, I. Thomas, C. Peters, W. The importance of folate, zinc and antioxidants in the pathogenesis and prevention of subfertility. Human Reprod Update. 2007;13(2):163-74. 3. Marieb, E. Essential of Human Anatomy and Physiology. 2003 7th ed. 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The effects of combined conventional treatment, oral anti oxidants and essential fatty acids on sperm biology in subfertile men. Prostglandins Leuko Essential Fatty Acids. 2000;63:159-65. 11. Lamond, S. Watkinson, M. Rutherford, T. Gene-specific chromatin damage in human spermatozoa can be blocked by antioxidants that target mitochondria. Reprod Biomed Online. 2003;7:407-41. 12. Balercia, G. Mancini, A. Paggi, F. et al. Coenzyme Q10 and male fertility. J Endocrinol Invest. 2009;32(7):626-32. 13. Mancini, A De Marinis, L. Littaru, G. Balercia, G. An update of coenzyme Q10 implications in male infertility: biochemical and therapeutic aspects. Biofactors. 2005;25(1-4):165-74. 14. Lenzi, A. Culasso, F. Gandini, L. et al. Andrology: Placebo controlled, double blind, cross-over trial of glutathione therapy in male infertility. Human Reprod. 1993;8(10):1657-62. 15. Kodama, H. Yamaguchi, R. Fukuda, J. et al. Increased oxidative deoxyribonucleic acid damage in the spermatozoa of infertile male patients. Fertil Steril. 1997;68:519-24. 16. Kessopoulou, E. Powers, H. Sharma, K. et al. A double blind randomized placebo cross-over controlled trial using the antioxidant vitamin E to treat reactive oxygen species associated male infertility. Fertil Steril. 1995;64(4):825-31. 17. Suleiman, S. Ali, M. Zaki, E. et al. Lipid peroxidation and human sperm motility: protective role of vitamin E. J Androl. 1996;17(5):530-7. 18. Rolf, C. Cooper, T. Yeung, C. Nieschlag, E. Antioxidant treatment of patients with asthenozoospermia or moderate oligoasthenozoospermia with high-dose vitamin C and vitamin E: a randomized, placebo controlled, double-blind study. Human Reprod. 1999;14(4):1028-33. 19. Safarinejad, M. Safarinejad, S. Efficacy of selenium and/or N-acetyl-cysteine for improving semen parameters in infertile men: a double blind, placebo controlled randomized study. J Urol. 2009;181(2):741-51. 20. National Health and Medical Research Council. Folate. 2005. [cited 2009, August 22], available from: www.nrv.gov.au/nutrients/folate.htm 21. Young, S. Eskanazi, B. Marchetti, F. The association of folate, zinc and antioxidant intake with sperm aneuploidy in healthy non-smoking men. Human Reprod. 2008;23(5):1014-22. 22. Wallock LM, Tamura T, Mayr CA, Johnston KE, Ames BN, Jacob RA. Low seminal plasma folate concentrations are associated with low sperm density and count in male smokers and non-smokers. Fertil Steril. 2001;75:252–9. 23. Boxmeer, J. Smit, M. Utomo, E. et al. Low folate in seminal plasma is associated with increased DNA damage. Fertil Steril. 2009;92(9):548-56. 24. Wong, W. Merkus, H. Thomas, C. et al. Effects of folic acid and zinc sulphate on male factor subfertility: a double-blind, randomized, placebo controlled trial. Fertil Steril. 2002;77(3):491-8. 25. Sorenson, M. Bergdahl, I. Hjolland, N. et al. Zinc magnesium and calcium in human seminal fluid: relations to other semen parameters. Molecular Human Reprod. 1999;5(4):331-7. 26. Riffo, M. Leiva, S. Astudillo, J. Effect of zinc on human sperm motility and the acrosome reaction. Int J Androl. 1992;15(3):229-37. 27. Liu, D. Sie, B. Liu, M. et al. Relationship between seminal plasma zinc concentration and spermatozoa-zona pellucida binding and the ZP-induced acrosome reaction in subfertile men. Asian J Androl. 2009;11:499-507. 28. NHMRC. Clinical Practice Guidelines for the Management of Overweight and Obesity in Adults; 2003. [cited 2009, May 26] Available from www.health.gov.au/internet/main/publishing.nsf/Content/obesityguidelines-guidelines-adults.htm
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